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Contents1Mode of action2Pharmacokinetics3Experimentation4Half-Life5Indications6Veterinary Uses7Contraindications7. 1absolute7. 2special caution needed8Side effects9Routine examinations needed under long-term treatment10Interactions11High Risk patients for abuse valium and. dependence12Withdrawal procedure after long-term treatment13Dose Recommendations14Dose Forms15Recreational Use16Overdose17Fatal Reaction18Occurrence in plants19Inventor20References edit Mode of actionIn. animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus,. and induces calming effects. It binds in to specific benzodiazepine receptors, which are part of the GABA-receptors. When diazepam binds to this receptor, it causes an increase in the inhibitory effects on. GABA. It is redistributed into tissues and fat deposits, and there is an adaptation of benzodiazepine. receptors. 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